Metastasis is a term from the Greek language whose translation into the English language means relocation. In cancer metastasis research, the phrase tumor metastasis is taken to refer to the process through which cancerous cells relocate from the initial place of development to other parts and organs. It is a substantially complicated process. The process is only understood in part in present day research. Studies at biochemical and molecular levels have not yet established a full comprehension of the process.
Surgery and radiation therapy can be used to adequately treat most cancers. The two treatment choices can either be used to remove or destroy the primary tumor successfully. However, what is contributing to mortality and morbidity in most cancer patients is the spread of tumor cells to secondary locations in the body. It would be very simple for the treatment of the disease to be done if only metastasis can be stopped from happening.
Scientists often make a comparison of the process of metastasis to marathon. Upon the development of malignant tissues, they begin to infest solid tissues around them. Body tissues contain a variety of cells and are very complex. For instance, body tissues have fibroblasts. These cells offer lymphatic drainage, support, and immune cells. They give a barrier that must be infiltrated by tumor cells. Malignant cells adapt to the presence of this barrier by developing the ability to move.
The movement of tumor cells does not happen in a strange way. The cells do not float out of a tissue. Instead, they crawl. They do this by basically reacting to factors within their environment. They extend finger-like extensions of their cell that allow them to move forward. To be able to move forward, they have to alter their ability to adhere to other cells in the body and the protein matrix.
Metastasis as indicated by research is very inefficient. Only 0.01 percent of the tumor cells that get into the blood stream finally metastasize. However, it is still impossible for researchers to establish when and if the tumor cells become metastatic. When being treated, cancer evaluation involves its ability to metastasize.
As a result, the patient gets treatment tailored to the capacity of the cancer they suffer from to become metastatic. Advanced cancers have an increased chance of getting metastatic when compared to early cancers. As such, progressive cancers are normally treated with more aggression as opposed to those in initial stages. Malignant cells normally get metastatic via two main avenues. These are lymphatic vessels and the bloodstream.
Numerous malignant cells have the tendency of making an escape via the lymphatic drainage system. This is the reason why doctors take lymphatic node biopsy. This they do to establish if there has been a spread of malignant cells already. The cells then make their way into the blood circulation from the lymphatic vessels. In addition to getting into the blood circulation, malignant cells may get into the blood flow from blood vessels directly.
Most tumor cells die when they enter the bloodstream as it is a very harsh environment. This is because it has immune cells and blood flows at a high speed. However, some end up in different organs where they grow into tumors.
Surgery and radiation therapy can be used to adequately treat most cancers. The two treatment choices can either be used to remove or destroy the primary tumor successfully. However, what is contributing to mortality and morbidity in most cancer patients is the spread of tumor cells to secondary locations in the body. It would be very simple for the treatment of the disease to be done if only metastasis can be stopped from happening.
Scientists often make a comparison of the process of metastasis to marathon. Upon the development of malignant tissues, they begin to infest solid tissues around them. Body tissues contain a variety of cells and are very complex. For instance, body tissues have fibroblasts. These cells offer lymphatic drainage, support, and immune cells. They give a barrier that must be infiltrated by tumor cells. Malignant cells adapt to the presence of this barrier by developing the ability to move.
The movement of tumor cells does not happen in a strange way. The cells do not float out of a tissue. Instead, they crawl. They do this by basically reacting to factors within their environment. They extend finger-like extensions of their cell that allow them to move forward. To be able to move forward, they have to alter their ability to adhere to other cells in the body and the protein matrix.
Metastasis as indicated by research is very inefficient. Only 0.01 percent of the tumor cells that get into the blood stream finally metastasize. However, it is still impossible for researchers to establish when and if the tumor cells become metastatic. When being treated, cancer evaluation involves its ability to metastasize.
As a result, the patient gets treatment tailored to the capacity of the cancer they suffer from to become metastatic. Advanced cancers have an increased chance of getting metastatic when compared to early cancers. As such, progressive cancers are normally treated with more aggression as opposed to those in initial stages. Malignant cells normally get metastatic via two main avenues. These are lymphatic vessels and the bloodstream.
Numerous malignant cells have the tendency of making an escape via the lymphatic drainage system. This is the reason why doctors take lymphatic node biopsy. This they do to establish if there has been a spread of malignant cells already. The cells then make their way into the blood circulation from the lymphatic vessels. In addition to getting into the blood circulation, malignant cells may get into the blood flow from blood vessels directly.
Most tumor cells die when they enter the bloodstream as it is a very harsh environment. This is because it has immune cells and blood flows at a high speed. However, some end up in different organs where they grow into tumors.
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