How Immunotherapy May Work Within Glioblastoma Research

By Rob Sutter


When you're talking about the more prevalent type of tumor in the brain, glioblastoma research is definitely something worth talking about. The potential that this method can possess is one of the greatest that I have seen. There is a high level of work done on the matter, which is tough to argue against. With so many stories posted about the matter, I would like to think that I have placed all of my attention on those which are the most deserving, of which there are many.

An article that was posted on Seeking Alpha talked about a 60-patient phase I/II trial about to be done. Northwest Biotherapeutics would be in charge as the process would be conducted at the MD Anderson Cancer Center. With the immunotherapy DCVax-Direct put into effect, it would grant patients a standard dose. This would then work into the Phase II portion of the experiment, which would then be able to determine a tumor shrinkage endpoint thanks to a RECIST measurement, which goes to show how complex the system is.

It seems like there is a number of features to consider but one of the biggest, in my eyes, has got to be the use of human cells. I'd like to refer you to stem cell research, which is done using a similar method. It seems like there is a great deal of attention placed on this matter because of how much information one's cells contain. While it seems like the parallels are obvious, I'd like to imagine that anyone who knows of these subjects can make them.

It seems easy enough to figure out why this method of glioblastoma research is being done today. While there are, at least, 120 types of tumors known, this particular variant is the most prevalent. It's the one that individuals are stricken with the most, as organizations along the lines of Voices against Brain Cancer will be able to tell you. I can only hope that the work done will be able to appeal to all of those who are afflicted, whether they are patients or not.

I believe that Northwest has done a great deal with this study, especially when it's been said that a phase III would be put into the place. The article mentioned that it would produce great data in 2014, which is hopefully accurate. After all, the work that has been done in terms of research has already been great, which means that even greater details will help it along even more so. It seems like a number of results will rise to the surface, which is hopefully the case in the future.




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