Brain Tumor Research & Human Cells In Mice

By Robert Sutter


Work in the medical field is going to be done in a number of different ways and typical procedures, at least the first few times around, are done with mice. They are able to react to certain treatments in particular ways, which gives a good idea of how humans are going to react to certain therapies. That being said, how can brain tumor research expand in such a way? It's a point to take into account and a recent story on the matter was successful in grabbing my attention.

A written piece on Science Daily talked about how John Hopkins researchers have brought an FDA-approved drug into effect for treatment of mice. What's interesting in the field of brain tumor research is that these mice had human growth cells inside of them. It's something to make note of, especially when it's been said that after the usage of such a drug, there was no trace of the cells in question. I'd like to think that this could be tremendous for organizations along the lines of Voices against Brain Cancer.

The story spoke about the IDH1 gene in particular, which was expanded upon back in 2008. This particular gene is seen in 70 to 80 percent of tumors and it is oftentimes mutated. One of the things to take into account is that, with said mutation brought into effect, the brain may not be able to put glucose to use, meaning that the energy typically brought from it cannot be utilized. As you can see, there are challenges to be had in this level of research.

It appears as though a number of different types of tumors are going to be focused on, which should be brought into account for every case. Not every growth is going to be the same, especially when you take into account all of the intricacies that one particular growth may have as opposed to another. Gliomas, for example, may be some of the most typical but does this necessarily mean that this one alone is going to be focused on? You will start to see many more in the medical field soon enough.

In my eyes, brain tumor research is one of those fields that have so much attention brought to it for the right reasons. Finding solid cures has proven to be a challenge but therapies seem to be built more and more over the course of time. It seems like some of them have proven to be successful, which has the case with this particular trial. Whether or not this will translate into human use remains to be seen but I am confident that results will rise to the surface.




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